Genetic Testing
Screening and Genetic Testing
Genetic Testing
Genetic testing is a special blood test that can help detect gene mutations that cause hereditary forms of cancer. Genetic testing looks for mutations in the Lynch
syndrome genes. Testing is usually performed on a blood sample. If a mutation is found, then the Lynch syndrome diagnosis is confirmed. In addition, genetic testing
may then be offered to other members of the family who wish to learn whether or not they have Lynch syndrome.
Genetic testing is best started in a family in a person who has already had cancer. If a hereditary condition is diagnosed, it can predict if that person could
be at risk for another type of cancer or if other members of their family could have the same gene mutation or not. In most cases, something can be done for a person
and/or their family members to help address the increased cancer risks.
Other Types of Testing
Specific pathology tests can be performed on a colon tumor or other tumor. These screening tests are called microsatellite instability (MSI) assay and
immunohistochemical (IHC) analysis. These tests look for characteristics in tumors that may be caused by Lynch syndrome, and can identify which gene may be
responsible for Lynch syndrome in the family. Genetic testing is recommended if the pathology results suggest the possibility of Lynch syndrome.
To make an appointment for a cancer genetic evaluation, please contact the
Clinical Cancer Genetics Program
at 713-745-7391.
|
|